CAS 915226-39-0, also known as Nintedanib or Ofev, is a potent and selective inhibitor of multiple tyrosine kinases, including vascular endothelial growth factor receptor (VEGFR), fibroblast growth factor receptor (FGFR), and platelet-derived growth factor receptor (PDGFR). This drug has been approved by the FDA for the treatment of idiopathic pulmonary fibrosis (IPF) and is also being investigated for the treatment of various cancers, such as ovarian, lung, and colorectal cancer.
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